منابع مشابه
Aquaporins and Brain Tumors
Brain primary tumors are among the most diverse and complex human cancers, and they are normally classified on the basis of the cell-type and/or the grade of malignancy (the most malignant being glioblastoma multiforme (GBM), grade IV). Glioma cells are able to migrate throughout the brain and to stimulate angiogenesis, by inducing brain capillary endothelial cell proliferation. This in turn ca...
متن کاملEgulation of Brain Aquaporins
bstract—Emerging evidence suggests that brain aquaporns (AQP) play important roles for the dynamic regulation of rain water homeostasis and for the regulation of cerebropinal fluid production. This review deals with the shortand ong-term regulation of AQP4 and AQP9, both expressed in strocytes, and of AQP1, expressed in the choroid plexus. QP1 and 4 have in other cell types been shown to be reg...
متن کاملAquaporins in brain: distribution, physiology, and pathophysiology.
Water homeostasis in the brain is of central physiologic and clinical importance. Neuronal activity and ion water homeostasis are inextricably coupled. For example, the clearance of K+ from areas of high neuronal activity is associated with a concomitant water flux. Furthermore, cerebral edema, a final common pathway of numerous neurologic diseases, including stroke, may rapidly become life thr...
متن کاملAquaporins in Brain Edema and Neuropathological Conditions
The aquaporin (AQP) family of water channels are a group of small, membrane-spanning proteins that are vital for the rapid transport of water across the plasma membrane. These proteins are widely expressed, from tissues such as the renal epithelium and erythrocytes to the various cells of the central nervous system. This review will elucidate the basic structure and distribution of aquaporins a...
متن کاملbrain tumors in elderly
brain tumors in elderly are increasing as the number of people, who comprise the older population, does.about half of the patients with brain tumors appear to be over 60 years of age.in this review article, glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential di...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2016
ISSN: 1422-0067
DOI: 10.3390/ijms17071029